組織学的研究支援室実績

論文

Satoshi Ikeo, Yuki Yamamoto , Kazuhiro Ikeda , Naoyuki Sone , Yohei Korogi , Lucia Tomiyama , Hisako Matsumoto , Toyohiro Hirai , Masatoshi Hagiwara , Shimpei Gotoh.
Core-shell hydrogel microfiber-expanded pluripotent stem cell-derived lung progenitors applicable to lung reconstruction in vivo.
Biomaterials, 2021 Sep;276:121031
doi: 10.1016/j.biomaterials.2021.121031
Takafumi Niwamoto, Tomohiro Handa , Yuko Murase , Yoshinari Nakatsuka , Kiminobu Tanizawa , Yoshio Taguchi , Hiromi Tomioka , Keisuke Tomii , Hideo Kita , Michihiro Uyama , Michiko Tsuchiya, Masahito Emura, Tetsuji Kawamura , Naoki Arai , Machiko Arita , Kazuko Uno , Akihiko Yoshizawa, Ryuji Uozumi, Izumi Yamaguchi , Fumihiko Matsuda, Kazuo Chin , Toyohiro Hirai.
Cutaneous T-cell-attracting chemokine as a novel biomarker for predicting prognosis of idiopathic pulmonary fibrosis: a prospective observational study.
Respir Res, 2021 Jun17;22(1):181
doi: 10.1186/s12931-021-01779-9
Ryoji Kawakami , Yohko Kitagawa , Kelvin Y Chen , Masaya Arai , Daiya Ohara , Yamami Nakamura , Keiko Yasuda , Motonao Osaki , Norihisa Mikami , Caleb A Lareau , Hitomi Watanabe , Gen Kondoh , Keiji Hirota , Naganari Ohkura , Shimon Sakaguchi.
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells.
Immunity, 2021 May 11;54(5):947-961.e8
doi: 10.1016/j.immuni.2021.04.005
Tomoko Kato Norio Harada , Eri Ikeguchi-Ogura , Akiko Sankoda , Tomonobu Hatoko , Xuejing Lu , Takuma Yasuda , Shunsuke Yamane , Nobuya Inagaki
J Mol Endocrinol 2021 Jan;66(1):11-22
Masuda N, Murakami K, Kita Y, Hamada A, Kamada M, Teramoto Y, Sakatani T, Matsumoto K, Sano T, Saito R, Okuno Y, Ogawa O, Kobayashi T.
Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates the Development of Basal Squamous-Like Invasive Bladder Cancer in the Chemical Carcinogenesis of Mouse Bladder.
Am J Pathol, 2020 Aug;190(8):1752-1762
doi: 10.1016/j.ajpath.2020.04.005
Satoshi Ogawa, Ueda M, Kono J, Sano T, Nishikawa N, Kunisue S, Tsujihana K, Liou LS, Kanematsu A, Shimba S, Doi M, Okamura H, Ogawa O, Negoro H.
“Epub 2020 Apr 28. SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice”.
Gastroenterology, 2020 Aug;159(2):682-696.e13
doi: 10.1038/s41598-018-20379-0
Seiichiro Tada Takayuki Anazawa , Takero Shindo , Kei Yamane , Kenta Inoguchi , Nanae Fujimoto , Kazuyuki Nagai , Toshihiko Masui , Hideaki Okajima , Kyoichi Takaori , Shoichiro Sumi , Shinji Uemoto
The MEK Inhibitor Trametinib Suppresses Major Histocompatibility Antigen-mismatched Rejection Following Pancreatic Islet Transplantation
Transplant Direct 2020 Aug 12;6(9):e591
doi: 10.1097/TXD.0000000000001045
Ayana Kon , Toyonori Sakata , Masahiro M Nakagawa , Naotaka Nakazawa , Masanori Kakuta , Keisuke Kataoka , Haruhiko Koseki , Manabu Nakayama , Daisuke Morishita , Tatsuaki Tsuruyama , Ryunosuke Saiki , Akinori Yoda , Rurika Okuda , Tetsuichi Yoshizato , Kenichi Yoshida , Yusuke Shiozawa , Yasuhito Nannya , Shinichi Kotani , Yasunori Kogure , Nobuyuki Kakiuchi , Tomomi Nishimura , Hideki Makishima , Luca Malcovati , Akihiko Yokoyama , Kengo Takeuchi , Eiji Sugihara , Taka-Aki Sato , Masashi Sanada , Akifumi Takaori-Kondo , Mario Cazzola , Mineko Kengaku , Satoru Miyano , Katsuhiko Shirahige , Hiroshi I Suzuki , Seishi Ogawa
Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes
Cancer Discov 2020 Jun;10(6):836-853
doi: 10.1158/2159-8290.CD-19-0982
Hirotsugu Maekawa , Shunsuke Kawai , Megumi Nishio, Sanae Nagata , Yonghui Jin , Hiroyuki Yoshitomi , Shuichi Matsuda , Junya Toguchida
Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1
Orphanet J Rare Dis 2020 May 24;15(1):122
doi: 10.1186/s13023-020-01406-8
Masahiro Kimura , Takahiro Horie , Osamu Baba , Yuya Ide , Shuhei Tsuji , Randolph Ruiz Rodriguez , Toshimitsu Watanabe , Tomohiro Yamasaki , Chiharu Otani , Sijia Xu , Yui Miyasaka 1, Yasuhiro Nakashima 1, Takeshi Kimura 1, Koh Ono 1
Homeobox A4 suppresses vascular remodeling by repressing YAP/TEAD transcriptional activity
EMBO Rep 2020 Apr 3;21(4)e48389
doi: 10.15252/embr.201948389
Kaoru Abiko, Noriomi Matsumura, Tsukasa Baba, Junzo Hamanishi , Ken Yamaguchi , Ryusuke Murakami, Mana Taki, Masayo Ukita, Yuko Hosoe, Masafumi Koshiyama, Ikuo Konishi, Masaki Mandai Br
Anti-VEGF therapy resistance in ovarian cancer is caused by GM-CSF-induced myeloid-derived suppressor cell recruitment
J Cancer 2020 Mar;122(6):778-788.
doi: 10.1038/s41416-019-0725-x
Hiroaki Ozasa , Wataru Aoki , Shunsuke Aburaya , Tomoko Yamamoto Funazo , Koh Furugaki , Yasushi Yoshimura , Masatoshi Yamazoe , Hitomi Ajimizu , Yuto Yasuda , Takashi Nomizo , Hironori Yoshida , Yuichi Sakamori 1, Hiroaki Wake 5, Mitsuyoshi Ueda 3, Young Hak Kim 1, Toyohiro Hirai 1
YAP1 mediates survival of ALK – rearranged lung cancer cells treated with alectinib via pro-apoptotic protein regulation
Nat Commun 2020 Jan3;11(1):74
doi:10.1038/s41467-019-13771-5
Kita Y, Hamada A, Saito R, Teramoto Y, Tanaka R, Takano K, Nakayama K, Murakami K, Matsumoto K, Akamatsu S, Yamasaki T, Inoue T, Tabata Y, Okuno Y, Ogawa O, Kobayashi T.
Systematic chemical screening identifies disulfiram as a repurposed drug that enhances sensitivity to cisplatin in bladder cancer: a summary of preclinical studies
Br J Cancer 2019 Dec;121(12):1027-1038
doi: 10.1038/s41416-019-0609-0
Yoshika Iwata , Kenichiro Tatsumi , Yoshimitsu Miyai , Tomonori Matsuyama , Tomoharu Tanaka
Maternal exposure to volatile anesthetics induces IL-6 in fetal brains and affects neuronal development
Eur J Pharmacol 2019 Nov 15;863:172682
doi: 10.1016/j.ejphar.2019.172682
Saori Goto , Koya Hida , Nobuaki Hoshino , Shigeo Hisamori , Kenji Kawada , Takaki Sakurai , Yoshiharu Sakai Asian
Laparoscopic rectal tumor surgery after administration of a new sclerosing therapy (aluminum potassium sulfate and tannic acid injection) for internal hemorrhoids: A report of three cases
J Endosc Surg 2019 Oct;12(4):473-477
doi:10.1111/ases.12664
Tsukasa Baba, Kaoru Abiko, Junzo Hamanishi, Ken Yamaguchi, Ryusuke Murakami, Mana Taki, Yuko Hosoe, Susan K Murphy, Ikuo Konishi, Masaki Mandai, Noriomi Matsumura
Acquisition of a side population fraction augments malignant phenotype in ovarian cancer
Sci Rep 2019 Oct 2;9(1):14215
doi: 10.1038/s41598-019-50794-w
Tsukasa Baba, Junzo Hamanishi, Noriomi Matsumura, Budiman Kharma, Yuka Mise, Kaoru Abiko , Ken Yamaguchi , Naoki Horikawa, David G Hunstman, Kumuluzi Mulati, Sachiko Kitamura, Mana Taki, Ryusuke Murakami, Yuko Hosoe, Masaki MandaiInt
Phosphorylation of STAT1 serine 727 enhances platinum resistance in uterine serous carcinoma
J Cancer 2019 Sep 15;145(6):1635-1647
doi: 10.1002/ijc.32501
Isao Hirabayashi, A Richard Palmer
Remarkably loud snaps during mouth-fighting by a sponge-dwelling worm
Curr Biol 2019 Jul8;29(13):R617-R618
doi:10.1016/j.cub.2019.05.047
Tomohiro Handa , Ran Nakashima , Kiminobu Tanizawa , Takeshi Kubo , Yuko Murase , Akihiko Sokai , Kohei Ikezoe , Yuji Hosono , Kizuku Watanabe , Shinsaku Tokuda , Kazuko Uno , Akihiko Yoshizawa , Tatsuaki Tsuruyama , Ryuji Uozumi , Sonoko Nagai , Kazuhiro Hatta , Yoshio Taguchi , Michiaki Mishima , Kazuo Chin , Tsuneyo Mimori , Toyohiro Hirai
Serum matrix metalloproteinase levels in polymyositis/dermatomyositis patients with interstitial lung disease
Rheumatology (Oxford) 2019 Mar8;kez065
doi: 10.1093/rheumatology/kez065
Junzo Hamanishi, Noriomi Matsumura, Kenji Chamoto, Nathan Mise, Kaoru Abiko, Tsukasa Baba, Ken Yamaguchi , Naoki Horikawa, Ryusuke Murakami, Mana Taki, Kharma Budiman, Xiang Zeng, Yuko Hosoe, Miyuki Azuma, Ikuo Konishi, Masaki Mandai
VISTA expressed in tumour cells regulates T cell function
Br J Cancer 2019 Jan;120(1):115-127
doi: 10.1038/s41416-018-0313-5
Uegaki M, Kita Y, Shirakawa R, Teramoto Y, Kamiyama Y, Saito R, Yoshikawa T, Sakamoto H, Goto T, Akamatsu S, Yamasaki T, Inoue T, Suzuki A, Horiuchi H, Ogawa O, Kobayashi T.
Downregulation of RalGTPase-activating protein promotes invasion of prostatic epithelial cells and progression from intraepithelial neoplasia to cancer during prostate carcinogenesis.
Carcinogenesis 2019 May 6. pii: bgz082
doi: 10.1093/carcin/bgz082
Miyazaki Y, Teramoto Y, Shibuya S, Goto T, Okasho K, Mizuno K, Uegaki M, Yoshikawa T, Akamatsu S, Kobayashi T, Ogawa O, Inoue T
Consecutive Prostate Cancer Specimens Revealed Increased Aldo⁻Keto Reductase Family 1 Member C3 Expression with Progression to Castration-Resistant Prostate Cancer.
J Clin Med 2019 May 1;8(5). pii: E601
doi: 10.3390/jcm8050601
Koichiro Hata , Yusuke Okamura , Yermek Nigmet , Hirofumi Hirao , Toyonari Kubota 1, Osamu Inamoto , Jiro Kusakabe , Toru Goto , Tetsuya Tajima , Junichi Yoshikawa , Hirokazu Tanaka , Tatsuaki Tsuruyama , Rene H Tolba , Shinji Uemoto
Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury
Liver Transpl 2018 Nov;24(11):1589-1602
doi: 10.1002/lt.25326Hydrogen
Funada S, Kita Y,Yoshiyuki Okada, Takashi Kobayashi, Yuki Teramoto, Shinsuke Shibuya, Ryoichi Saito, Kaoru Murakami, Keiyu Matsumoto, Yang Feng, Dimiter S. Dimitrov, Takahiro Inoue, Osamu Ogawa
Bladder urothelial carcinoma producing insulin‐like growth factor II: A case report
IJU Case reports 2018 Sep; 1(1): 9-12
doi: 10.1002/iju5.12018
Kaoru Abiko, Tsukasa Baba, Junzo Hamanishi, Ken Yamaguchi, Ryusuke Murakami, Koji Yamanoi, Naoki Horikawa, Yuko Hosoe, Eijiro Nakamura, Aiko Sugiyama, Masaki Mandai, Ikuo Konishi, Noriomi Matsumura
Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
Nat Commun 2018 Apr 27;9(1):1685
doi: 10.1038/s41467-018-03966-7
Shuang Wei, Elaine M Hurt, Michael D Green, Lili Zhao, Linda Vatan, Wojciech Szeliga, Ronald Herbst, Paul W Harms, Leslie A Fecher, Pankaj Vats, Arul M Chinnaiyan, Christopher D Lao, Theodore S Lawrence, Max Wicha, Junzo Hamanishi, Masaki Mandai, Ilona Kryczek, Weiping Zou
Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression
J Clin Invest 2018 Apr 2;128(4):1708
doi: 10.1172/JCI120803
Sengiku A,Ueda M, Kono J, Sano T, Nishikawa N, Kunisue S, Tsujihana K, Liou LS, Kanematsu A, Shimba S, Doi M, Okamura H, Ogawa O, Negoro H.
Circadian coordination of ATP release in the urothelium via connexin43 hemichannels.
Sci Rep 2018 Jan 31;8(1):1996
doi: 10.1038/s41598-018-20379-0
Jungmi Choi , Hatasu Kobayashi , Hiroko Okuda , Kouji H Harada , Midori Takeda , Hiroyuki Fujimoto , Shunsuke Yamane , Daisuke Tanaka , Shohab Youssefian , Nobuya Inagaki , Akio Koizumi
β-cell-specific overexpression of adiponectin receptor 1 does not improve diabetes mellitus in Akita mice
PLoS One 2018 Jan 5;13(1):e0190863
doi: 10.1371/journal.pone.0190863
Tomohiro Aoki , Hirokazu Koseki , Miyuki Fukuda , Jun Hirose , Keiichi Tsuji , Katsumi Takizawa , Shinichiro Nakamura , Haruka Miyata , Nozomu Hamakawa , Hidetoshi Kasuya , Kazuhiko Nozaki , Yoshitaka Hirayama, Ichiro Aramori , Shuh Narumiya
A sphingosine-1-phosphate receptor type 1 agonist, ASP 4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration
Br J Pharmacol 2017 Jul;174(13):2085-2101
doi:10.1111/bph.13820
Kaoru Abiko, Noriomi Matsumura, Junzo Hamanishi, Tsukasa Baba, Ken Yamaguchi, Yumiko Yoshioka, Masafumi Koshiyama, Ikuo Konishi
CCR-16-0387Expression of Vascular Endothelial Growth Factor in Ovarian Cancer Inhibits Tumor Immunity through the Accumulation of Myeloid-Derived Suppressor Cells
Clin Cancer Res 2017 Jan 15;23(2):587-599
doi: 10.1158/1078-0432

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